Tisgaon lies on the
Ahmednagar-Shevgaon route, on state Highway 148, in
Ahmednagar District.
Miri lies 15 km north-west of Tisgaon and Pathardi is 12 km south-east. Ahmednagar, the district headquarters, is 38 km south-west of Tisgaon.
The historic Mughal edifices and Ahmednagar Fort at Ahmednagar and Seclusion Hill are tourist sites in the immediate reach.
Aurangabad Airport and Ahmednagar Railway Station serve Tisgaon.