Situated in the center of Mananthavady town, Mananthavady Bus Station is a major bus terminal in Wayanad District. There are regular services to Kozhikode, Kannur, Payyanur, Thalassery, Sulthan Bathery and Kalpetta. Inter-state buses are run from Mananthavady to Karnataka. Local services are also available to various places in the district. Kerala State Road Transport Corporation operates super fast, fast passenger and ordinary buses from here.
Places of tourist interest in the town include Pazhassi Raja Tomb, Pazhassi Tourist Resort and Valliyoorkkavu Bhagavathi Temple. PWD Rest House, Forest Rest House and Forest Inspection Bungalow provide accommodation in Mananthavady.